Formulation: A solid
Formal Name: N-[(1R,4Z,8S,13E)-8-[[4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyranosyl]oxy]amino]-2-O-[2,4-dideoxy-4-(ethylamino)-3-O-methyl-α-L-threo-pentopyranosyl]-β-D-glucopyranosyl]oxy]-1-hydroxy-13-[2-(methyltrithio)ethylidene]-11-oxobicyclo[7.3.1]trideca-4,9-diene-2,6-diyn-10-yl]-carbamic acid, methyl ester
Purity: ≥95%
Formula Markup: C55H74IN3O21S4
Formula Weight: 1368,3
Shelf life (days): 1460
CAS Number: 108212-75-5
Notes: Calicheamicin γ1 is a polyketide synthase-derived enediyne that has been found in M. echinospora.{69845} It is composed of carbohydrate and aromatic moieties, which bind to the minor groove in DNA, and a warhead moiety that aromatizes and oxidatively induces double-stranded DNA scission in cell-free assays.{69846,69847}
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