(−)-Catechin Gallate, CAS 130405-40-2

Formulation: A crystalline solid

Formal Name: 3,4,5-trihydroxy-(2S,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester, benzoic acid

Purity: ≥98%

Formula Markup: C22H18O10

Formula Weight: 442,4

Shelf life (days): 1460

CAS Number: 130405-40-2

Notes: (–)-Catechin gallate ((–)-CG) is a catechin polyphenol that has been found in green tea extracts with diverse biological activities.{41817,41815,41818,41816} It inhibits proliferation of MDA-MB-231 breast cancer cells and reduces VEGF-induced tyrosine phosphorylation of VEGF receptor 2 (VEGFR2) in bovine aortic endothelial cells (BAECs) in a concentration-dependent manner.{41817,41815} (–)-CG is a competitive inhibitor of the facilitative glucose transporter GLUT4 (Ki = 90 μM) and inhibits methylglucose uptake by isolated rat adipocytes (IC50 = 50 μM).{41818} It is also lytic against T. cruzi amastigotes, with a 50% bactericidal concentration (MBC50) value of 48 pM.{41816}

• Artikelnummer: CAY24963-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24963-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK