Caudatin, CAS 38395-02-7

Formulation: A solid

Formal Name: (3β,12β,14β,17α)-12-[[(2E)-3,4-dimethyl-1-oxo-2-pentenyl]oxy]-3,8,14,17-tetrahydroxy-pregn-5-en-20-one

Purity: ≥98%

Formula Markup: C28H42O7

Formula Weight: 490,6

Shelf life (days): 1460

CAS Number: 38395-02-7

Notes: Caudatin is a C-21 steroid that has been found in C. auriculatum and has anticancer activity.{63178,63179} It is cytotoxic to SMMC-7721, MCF-7, and HeLa cells (IC50s = 24.95, 65.82, and 247.54 µM, respectively).{63178} Caudatin (50-300 µM) induces apoptosis in and inhibits mammosphere formation by MDA-MB-231 breast cancer cells, as well as decreases the number of cancer stem cells (CSCs) in the MDA-MB-231 cell population.{63179} In vivo, caudatin (10 mg/kg) reduces tumor volume in an MDA-MB-231 mouse xenograft model.

• Artikelnummer: CAY34585-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34585-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK