CAY10580, CAS 64054-40-6

Formulation: A solution in ethanol

Formal Name: 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid

Purity: ≥96%

Formula Markup: C19H35NO4

Formula Weight: 341,5

Shelf life (days): 365

CAS Number: 64054-40-6

Notes: Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis.{16772,16773,16619} CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It selectively binds the EP4 receptor (Ki = 35 nM) relative to the EP1, EP2, and EP3 receptors (Ki = 3,000, 2,000, and >3,000 nM, respectively).{16762} CAY10580 stimulates cAMP formation in excised mouse ovaries.{16763}

• Artikelnummer: CAY16835-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16835-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK