CAY10726, CAS 1611446-66-2

Formulation: A crystalline solid

Formal Name: 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoic acid

Purity: ≥98%

Formula Markup: C24H36ClF3N2O3

Formula Weight: 493

Shelf life (days): 730

CAS Number: 1611446-66-2

Notes: CAY10726 is an arylurea fatty acid.{40512} It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 μM. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

• Artikelnummer: CAY23859-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23859-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK