Cholic Acid, CAS 81-25-4

Formulation: A crystalline solid

Formal Name: (5β)-3α,7α,12α-trihydroxy-cholan-24-oic acid

Purity: ≥95%

Formula Markup: C24H40O5

Formula Weight: 408,6

Shelf life (days): 1460

CAS Number: 81-25-4

Notes: Cholic acid is a primary bile acid.{52692} It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA; Item No. 20276) and taurocholic acid (TCA; Item No. 16215), respectively, in the liver, and is transformed into the secondary bile acid deoxycholic acid (DCA; Item No. 20756) by intestinal microbiota.{52692,61155,61156} It induces C. difficile colony formation in an agar dilution assay when used at a concentration of 0.1% w/v.{61157} Dietary administration of cholic acid (0.4% w/w) increases serum cholesterol levels, biliary phospholipid secretion, and fecal DCA levels in rats.{61158}

• Artikelnummer: CAY20250-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20250-500
• Green Labware: Nein
• Verpackungseinheit: 500 g
• Mengeneinheit: STK