Chrysin 7-Glucuronide, CAS 35775-49-6

Formulation: A solid

Formal Name: 5-hydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid

Purity: ≥98%

Formula Markup: C21H18O10

Formula Weight: 430,4

Shelf life (days): 1460

CAS Number: 35775-49-6

Notes: Chrysin 7-glucuronide is a flavonoid glucuronide that has been found in S. baicalensis and has diverse biological activities and is an active metabolite of chrysin (Item No. 17402).{58797,58798,58799,58800} It is formed from chrysin by various UDP-glucuronosyltransferase (UGT) isoforms, including UGT1A3, UGT1A6, and UGT1A9.{58800} Chrysin 7-glucuronide inhibits α-glucosidase, α-amylase, and neuraminidase (IC50s = 612, 980, and 428 µg/ml, respectively).{58797,58798} It also inhibits organic anion transporting polypeptide (OATP) isoforms OATP1A2, OATP1B1, OATP1B3, and OATP2B1 (IC50s = 24.1, 4.4, 14.3, and 0.3 µM, respectively), as well as breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 2 (MRP2; IC50s = 19.8 and 11.2 µM, respectively).{58799}

• Artikelnummer: CAY35034-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35034-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK