Clarithromycin-13C-d3, CAS 2699608-30-3

Formulation: A solid

Formal Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methyl(methyl-13C-d3)amino)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C37[13C]H66D3NO13

Formula Weight: 752

Shelf life (days): 1460

CAS Number: 2699608-30-3

Notes: Clarithromycin-13C-d3 is intended for use as an internal standard for the quantification of clarithromycin (Item No. 19455) by GC- or LC-MS. Clarithromycin is a polyketide synthase-derived semisynthetic macrolide antibiotic.{31455,22680,60822} It is active against methicillin-susceptible, but not methicillin-resistant, S. aureus (MIC50s = 0.06 and >128 µg/ml), S. pyogenes, L. monocytogenes, and B. pertussis (MIC50 = 0.015, 0.25, and ≤0.008 µg/ml, respectively), among others.{31455} Clarithromycin (25 mg/kg) decreases the number of colony-forming units (CFUs) in the spleen in a mouse model of M. avium infection.{60823} Formulations containing clarithromycin have been used in the treatment of bacterial infections and, when used in combination with other antibiotics, in the treatment of H. pylori.

• Artikelnummer: CAY26678-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26678-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung