Formulation: A solution in ethanol
Formal Name: 6-methylheptyl 7-(2-((3-((2-butyloctyl)oxy)-3-oxopropyl)thio)ethyl)-2-methyl-14-((3-((6-methylheptyl)oxy)-3-oxopropyl)thio)-6,9-dioxo-17-thia-2,5,8-triazaicosan-20-oate
Purity: ≥95%
Formula Markup: C53H101N3O8S3
Formula Weight: 1004,6
Shelf life (days): 730
Notes: Lipid CP-LC-1428 is an ionizable cationic amino lipid derived from homocysteine, a naturally occurring amino acid. This lipid has demonstrated an efficient delivery and high protein expression of different kinds of RNA (mRNA, cRNA and saRNA) in vivo. Moreover, using a typical LNP formulation (IL/Ch/DOPE/PEG: 50/38.5/10/1.5), it has shown to induce specific spleen targeting much more efficiently that other commercial alternatives through IV injection, with no signs of toxicity.