Cytochalasin H, CAS 53760-19-3

Formulation: A lyophilisate

Formal Name: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-1H-cycloundec[d]isoindol-1-one

Purity: ≥95%

Formula Markup: C30H39NO5

Formula Weight: 493,6

Shelf life (days): 1460

CAS Number: 53760-19-3

Notes: The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization.{21305,21310,21312,21316} This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.{21307,21313,21306,21315} Cytochalasin H is a potent inhibitor of actin incorporation into filaments.{25080,29763} Like cytochalasin D (Item No. 11330), it also increases the steady-state diffusion coefficients of filaments, suggesting that it stimulates filament shortening.{25080} Cytochalasin H suppresses the production of reactive oxygen species by stimulated human neutrophils, blocks endocytosis of CD59 in lymphocytes, and shows anti-angiogenic activity both in vitro and in vivo.{29673,29761,29762}

• Artikelnummer: CAY18434-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18434-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK