Cytochalasin J, CAS 53760-20-6

Formulation: A lyophilisate

Formal Name: 2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one

Purity: ≥95%

Formula Markup: C28H37NO4

Formula Weight: 451,6

Shelf life (days): 1460

CAS Number: 53760-20-6

Notes: The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization.{21305,21310,21312,21316} This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion.{21307,21313,21306,21315} Cytochalasin J is a deacetylated analog of cytochalasin H that weakly inhibits actin assembly but significantly alters mitotic spindle microtubule organization and kinetochore structure.{25080,29674} Like cytochalasin H, cytochalasin J suppresses the production of reactive oxygen species by stimulated human neutrophils.{29673}

• Artikelnummer: CAY18443-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18443-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK