Notes: Decanoyl-coenzyme A (CoA) is a thioester of decanoic acid (Item No. 20838) and CoA (Item Nos. 16147 / 21499 / 21722).{45487} It inhibits the activity of citrate synthase (CS) and glutamate dehydrogenase (GDH) in mitochondria isolated from rat brain (IC50s = 437 and 420 µM, respectively).{45491} Decanoyl-CoA also binds the fatty acid metabolism regulator protein (FadR) promoter in E. coli (Ki = 2 µM).{45490} It is produced during isomerase-dependent β-oxidation of oleic acid (Item Nos. 90260 / 24659) in isolated rat heart mitochondria.{12936}