Formulation: A crystalline solid
Formal Name: 9-fluoro-11β,21-dihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Formula Markup: C22H29FO4
Formula Weight: 376,5
Shelf life (days): 1460
CAS Number: 382-67-2
Notes: Desoximetasone is a glucocorticoid.{39559} In vivo, desoximetasone (0.001-0.1 mg) reverses increases in epidermal cell proliferation induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in SENCAR mice when administered topically. It also reduces TPA-induced expression of IL-6, COX-2, iNOS, and c-Jun mRNA levels in the skin of SENCAR mice, indicating anti-inflammatory action. Formulations containing desoximetasone have been used in the treatment of psoriasis and atopic dermatitis.