Dexamethasone Palmitate, CAS 14899-36-6

Formulation: A solid

Formal Name: 9-fluoro-11β,17-dihydroxy-16α-methyl-21-[(1-oxohexadecyl)oxy]-pregna-1,4-diene-3,20-dione

Purity: ≥98%

Formula Markup: C38H59FO6

Formula Weight: 630,9

Shelf life (days): 1460

CAS Number: 14899-36-6

Notes: Dexamethasone palmitate is a prodrug form of the synthetic glucocorticoid dexamethasone (Item No. 11015).{62652} It binds to the glucocorticoid receptor.{62653} Dexamethasone palmitate-containing lipid nanoparticles reduce LPS-induced increases in cytokine levels in RAW 264.7 macrophages when used at a concentration of 100 µg/ml.{62654} Dexamethasone palmitate reduces paw inflammation and edema in a mouse model of collagen-induced rheumatoid arthritis when administered at a dose of 1 mg/kg. Intravitreal injection of a dexamethasone palmitate (1,280 µg/animal) emulsion inhibits vascular hyperpermeability induced by VEGF for up to nine months in rabbits.{62652}

• Artikelnummer: CAY35451-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35451-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe