Dexamethasone Phosphate (sodium salt), CAS 2392-39-4

Formulation: A crystalline solid

Formal Name: (11β,16α)-9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-pregna-1,4-diene-3,20-dione, disodium salt

Purity: ≥95%

Formula Markup: C22H28FO8P • 2Na

Formula Weight: 516,4

Shelf life (days): 1460

CAS Number: 2392-39-4

Notes: Dexamethasone phosphate is a glucocorticoid.{64722} It reduces LPS-induced production of RANTES, TGF-β1, and nitric oxide (NO) in BV-2 microglia when used at concentrations ranging from 1 to 4 µM. Dexamethasone phosphate reverses LPS-induced decreases in IL-10 levels in, and inhibits LPS-induced migration of, BV-2 microglia when used at a concentration of 4 µM. In vivo, dexamethasone phosphate decreases motor activity and reduces adrenal weight and plasma corticosterone levels in rats when administered in the drinking water at a concentration of 5 µg/ml.{64723} Dexamethasone phosphate (1.6 mg/kg per day) reduces joint swelling in a rat model of collagen-induced arthritis when administered for a minimum of seven days.{64724} It also reduces pruritis and the clinical lesion score in cats with hypersensitivity dermatitis.{64725} Formulations containing dexamethasone phosphate have been used in the treatment of various inflammatory diseases, arthritis, and endocrine disorders.

• Artikelnummer: CAY20340-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20340-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK