Diosmetin, CAS 520-34-3

Formulation: A crystalline solid

Formal Name: 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C16H12O6

Formula Weight: 300,3

Shelf life (days): 1460

CAS Number: 520-34-3

Notes: Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities.{30253,49507,49508,49509} It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively).{30253} Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced by AAPH (Item No. 82235) in a concentration-dependent manner.{49507} It reduces tumor growth and tumor blood vessel density in a B16/F10 murine melanoma model when administered at a dose of 1 mg/kg twice per day.{49508} Diosmetin (0.5 mg/kg) inhibits lung goblet cell hyperplasia and collagen deposition and decreases the number of eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) in a mouse model of chronic asthma induced by ovalbumin.{49509}

• Artikelnummer: CAY18649-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 18649-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK