Drospirenone-13C3

Formulation: A solid

Formal Name: (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR,8dR,9aR)-4a,6a-dimethyl-3',4,4a,4b,4',5,6,6a,7a,8,8a,8b,8c,8d,9,9a-hexadecahydro-5'H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthrene-7,2'-furan]-2,5'(3H)-dione-3',4',5'-13C3

Purity: ≥95%

Formula Markup: C21[13C]3H30O3

Formula Weight: 369,5

Shelf life (days): 1460

Notes: Drospirenone-13C3 is intended for use as an internal standard for the quantification of drospirenone (Item No. 23347) by GC- or LC-MS. Drospirenone is a synthetic progestogen.{41140} In vivo, drospirenone inhibits spontaneous ovulation in rats (ID50s = 0.3-1.0 mg/day) when administered orally or subcutaneously.{41141} Drospirenone (0.5 mg/animal) administered six times per day maintains pregnancy in ovariectomized pregnant rats. It reduces serum testosterone and luteinizing hormone (LH) in cynomolgus monkeys in a dose-dependent manner. Drospirenone (10 mg/animal per day) also inhibits testosterone-induced growth of the seminal vesicles and prostate in castrated rats. Formulations containing drospirenone have been used as oral contraceptives.{41142}

• Artikelnummer: CAY34008-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34008-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung