(E)-2-Hexadecenal, CAS 22644-96-8

Formulation: A crystalline solid

Formal Name: (2E)-2-hexadecenal

Purity: ≥95%

Formula Markup: C16H30O

Formula Weight: 238,4

Shelf life (days): 1460

CAS Number: 22644-96-8

Notes: Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal is a sphingolipid degradation product resulting from the action of S1P lyase. It can be further oxidized to (2E)-hexadecenoic acid by long-chain fatty aldehyde dehydrogenase prior to activation via coupling to coenzyme A. (E)-2-Hexadecenal has been shown to induce cytoskeletal reorganization that results in cell rounding, detachment, activation of downstream JNK targets, and eventual apoptosis in various cell types.{28538} It reacts readily with deoxyguanosine and DNA to form aldehyde-derived DNA adducts.{28539}

• Artikelnummer: CAY17566-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 17566-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK