Formulation: A solution in acetonitrile
Formal Name: 9β,11β,15S-trihydroxy-(12β)-prosta-5Z,13E-dien-1-oic acid
Purity: ≥98%
Formula Markup: C20H34O5
Formula Weight: 354,5
Shelf life (days): 365
CAS Number: 214748-66-0
Notes: Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively.{14005} This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.{14928}