Formulation: A solution in acetonitrile
Formal Name: 9β,11β,15R-trihydroxy-(12α)-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Purity: ≥99% deuterated forms (d1-d9)
Formula Markup: C20H25D9O5
Formula Weight: 363,5
Shelf life (days): 365
Notes: ent-8-iso-Prostaglandin F2α-d9 (ent-8-iso-PGF2α-d9) is intended for use as an internal standard for the quantification of ent-8-iso-PGF2α (Item No. 10011545) by GC- or LC-mass spectrometry. Isoprostanes are produced by the non-enzymatic, free-radical peroxidation of arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have a potent biological activity. ent-8-iso PGF2α is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 31 and 54 nM, respectively.{14005}