(−)-Epicatechin, CAS 490-46-0

Formulation: A crystalline solid

Formal Name: 2R-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3R,5,7-triol

Purity: ≥90%

Formula Markup: C15H14O6

Formula Weight: 290,3

Shelf life (days): 1460

CAS Number: 490-46-0

Notes: (−)-Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities.{63044,23115,15205,23116,63045} It scavenges DPPH (Item No. 14805) radicals in a cell-free assay when used at a concentration of 5 µM.{23115} (−)-Epicatechin inhibits COX-1 (IC50 = 3.2 μM).{50297} It acts synergistically with epigallocatechin gallate (Item No. 70935) to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 µM.{23116} (−)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.{63045}

• Artikelnummer: CAY11807-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11807-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK