Formulation: A crystalline solid
Formal Name: 3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
Purity: ≥98%
Formula Markup: C15H14O3
Formula Weight: 242,3
Shelf life (days): 1460
CAS Number: 94105-90-5
Notes: Equol is a nonsteroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.{16628,16720} The estrogen receptor (ER) binding activity of the naturally occurring (S)-enantiomer demonstrates greater affinity toward ERβ while the (R)-enantiomer demonstrates greater affinity towards ERα.{16628,16720} Synthesized as a racemic mixture, (±)-equol exhibits EC50 values of 200 and 74 nM for human ERα and ERβ, respectively and induces breast cancer cell proliferation in vitro at concentrations as low as 100 nM.{16720,17383}