Estradiol 3-(β-D-Glucuronide) (sodium salt), CAS 14982-12-8

Formulation: A crystalline solid

Formal Name: (17β)-17-hydroxyestra-1,3,5(10)-trien-3-yl β-D-glucopyranosiduronic acid, monosodium salt

Purity: ≥95%

Formula Markup: C24H31O8 • Na

Formula Weight: 470,5

Shelf life (days): 1460

CAS Number: 14982-12-8

Notes: Estradiol 3-(β-D-glucuronide) (E23G) is a non-cholestatic regioisomer of the estrogen metabolite, estradiol 17-(β-D-glucuronide) (E217G; Item No. 16156).{26342,26341} It acts as a substrate for multidrug resistance protein 2 (MRP2; Km = 122 µM), competing with E217G for MRP2-mediated transport (IC50 = 14.2 µM).{26341,26340} E23G has been reported to inhibit E217G transport through rat organic anion-transporting polypeptide 1 with a Ki value of 9.7 µM, but is a low-affinity inhibitor of both MRP4 and MRP7 (IC50s = ~ 100 µM).{26341}

• Artikelnummer: CAY16155-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 16155-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK