Formulation: A solid
Formal Name: 16α,17β-dihydroxyestra-1,3,5(10)-trien-3-yl, β-D-glucopyranosiduronic acid, monosodium salt
Purity: ≥95%
Formula Markup: C24H32O9 • Na
Formula Weight: 487,5
Shelf life (days): 1460
CAS Number: 15087-06-6
Notes: Estriol 3-β-D-glucuronide is a metabolite of estriol (Item No. 10006484).{43880} It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membranes with Kd values of 85 and 164 µM, respectively.{43881} It competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide (4Mu-GlcU; Item No. 17203) and is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc).{14585}