Formulation: A solid
Formal Name: 3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt
Purity: ≥95%
Formula Markup: C18H21O5S • Na
Formula Weight: 372,4
Shelf life (days): 1460
CAS Number: 438-67-5
Notes: Estrone 3-sulfate is an endogenous steroid that is converted into estrone (Item No. 10006485) in vivo.{32192} It inhibits organic anion transport polypeptide 1B1 (OATP1B1) and is selective for OATP1B1 over OATP1B3 (IC50s = 0.06 and 19.3 µM, respectively).{41286} Formulations containing estrone 3-sulfate have been used in the treatment of menopausal symptoms and for the prevention of osteoporosis in high-risk populations.