Estrone-d2, CAS 350820-16-5

Formulation: A crystalline solid

Formal Name: 3-hydroxy-estra-1,3,5(10)-trien-17-one-2,4-d2

Purity: ≥98%

Formula Markup: C18H20D2O2

Formula Weight: 272,4

Shelf life (days): 1460

CAS Number: 350820-16-5

Notes: Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165 / 10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155 / 10006315) and estriol (Item Nos. ISO60164 / 10006484).{9611} Estrone is synthesized from androstenedione (Item No. 9001311) by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.{9611,8343} Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women.{9611} The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.{9611}

• Artikelnummer: CAY9002844-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9002844-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung