Formulation: A solid
Formal Name: 3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, compd. with piperazine
Purity: ≥98%
Formula Markup: C18H22O5S • C4H10N2
Formula Weight: 436,6
Shelf life (days): 1460
CAS Number: 7280-37-7
Notes: Estropipate is a piperazine salt form of estrone 3-sulfate (Item No. 36989), which is an endogenous steroid that is converted into estrone (Item No. 10006485) in vivo.{32192} Estropipate is also an inhibitor of organic anion transport polypeptide 1B1 (OATP1B1) that is selective for OATP1B1 over OATP1B3 (IC50s = 0.06 and 19.3 µM, respectively).{41286} Formulations containing estropipate have been used in the treatment of menopausal symptoms and for the prevention of osteoporosis in high risk populations.