Exemestane, CAS 107868-30-4

Formulation: A crystalline solid

Formal Name: 6-methylene-androsta-1,4-diene-3,17-dione

Purity: ≥95%

Formula Markup: C20H24O2

Formula Weight: 296,4

Shelf life (days): 1460

CAS Number: 107868-30-4

Notes: Exemestane is an irreversible inhibitor of aromatase (Ki = 26 nM).{64846} It is selective for aromatase over 5α-reductase when used at a concentration of 30 µM. Subcutaneous administration of exemestane (3-100 mg/kg per day) decreases tumor proliferation in rats with mammary tumors induced by the carcinogenic polycyclic aromatic hydrocarbon 7,12-dimethylbenz(a)anthracene (DMBA; Item No. 30383).{64847} Formulations containing exemestane have been used in the treatment of estrogen receptor-positive breast cancers in postmenopausal women.

• Artikelnummer: CAY15008-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15008-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK