Fisetin, CAS 528-48-3

Formulation: A crystalline solid

Formal Name: 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one

Purity: ≥90%

Formula Markup: C15H10O6

Formula Weight: 286,2

Shelf life (days): 1460

CAS Number: 528-48-3

Notes: Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities.{61545,61546,61547,61548} It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP; Item No. 21495) in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM.{61545,61547} Fisetin (10-60 µM) induces cell cycle arrest at the G1 phase and apoptosis in, as well as inhibits the proliferation of, LNCaP prostate cancer cells.{61546} It inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and NF-κB activation in RAW 264.7 cells.{61547} Fisetin (1 mg/animal) reduces tumor growth in a CWR22Rυ1 prostate cancer mouse xenograft model.{61548}

• Artikelnummer: CAY15246-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 15246-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK