Fisetin-d5, CAS 2909407-29-8

Formulation: A solid

Formal Name: 2-(3,4-dihydroxyphenyl-2,5,6-d3)-3,7-dihydroxy-4H-1-benzopyran-4-one-6,8-d2

Purity: ≥99% deuterated forms (d1-d5)

Formula Markup: C15H5D5O6

Formula Weight: 291,3

Shelf life (days): 1460

CAS Number: 2909407-29-8

Notes: Fisetin-d5 is intended for use as an internal standard for the quantification of fisetin (Item No. 15246) by GC- or LC-MS. Fisetin is a flavonoid that has been found in various fruits and vegetables and has diverse biological activities.{61545,61546,61547,61548} It scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay and inhibits oxidative burst induced by N-Formyl-Met-Leu-Phe (fMLP; Item No. 21495) in isolated human polymorphonuclear neutrophils (PMNs) when used at a concentration of 10 µM.{61545,61547} Fisetin (10-60 µM) induces cell cycle arrest at the G1 phase and apoptosis in, as well as inhibits the proliferation of, LNCaP prostate cancer cells.{61546} It inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and NF-κB activation in RAW 264.7 cells.{61547} Fisetin (1 mg/animal) reduces tumor growth in a CWR22Rυ1 prostate cancer mouse xenograft model.{61548}

• Artikelnummer: CAY34706-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34706-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung