Formulation: A solution in ethanol
Formal Name: 5-oxo-6Z,9S-(S-glutathionyl)-11Z,14Z-eicosatrienoic acid
Purity: ≥98%
Formula Markup: C30H47N3O9S
Formula Weight: 625,8
Shelf life (days): 180
Notes: FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9. The biological activity of FOG9 has not been determined. However, FOG7, a 1,4-adduct formed within murine peritoneal macrophages, was found to be highly potent in stimulating eosinophil and neutrophil chemotaxis.{8518} FOG7 was also capable of initiating actin polymerization without elevating intracellular free calcium ion concentration within either the eosinophil neutrophils or PMNL.