Ganglioside GD3 (bovine buttermilk) (ammonium salt), CAS 62010-37-1

Formulation: A solid

Purity: ≥98%

Formula Markup: C75H133N3O29 • 2NH4 (for tricosanoyl)

Formula Weight: 1577

Shelf life (days): 1460

CAS Number: 62010-37-1

Notes: Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.{31218} It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM.{5033} Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro.{28470} Ganglioside GD3-deficient adult mice exhibit progressive loss of the neural stem cell (NSC) pool and impaired neurogenesis.{37782} This product contains ganglioside GD3 molecular species with primarily C23:0, C22:0, and C24:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya LLC., Catalog No. 1504]

• Artikelnummer: CAY31709-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31709-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK