Ganglioside GM3 (bovine buttermilk) (ammonium salt), CAS 54827-14-4

Formulation: A solid

Purity: ≥98%

Formula Markup: C64H117N2O21 • NH4 (for tricosanoyl)

Formula Weight: 1268,7

Shelf life (days): 1460

CAS Number: 54827-14-4

Notes: Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and pro-apoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.{25490,25485} It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation.{25490,25485} Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functioning as an inhibitor of insulin signaling and contributing to insulin resistance in adipocytes.{25481} This product contains ganglioside GM3 molecular species with primarily C22:0, C23:0, and C24:0 fatty acyl chain lengths. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1503]

• Artikelnummer: CAY31711-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31711-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK