Globotetraosylceramide (porcine RBC), CAS 11034-93-8

Formulation: A solid

Formal Name: 1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide

Purity: ≥98%

Formula Markup: C68H126N2O23 (for tetracosanoyl)

Formula Weight: 1339,7

Shelf life (days): 1460

CAS Number: 11034-93-8

Notes: Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes.{43016} They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19.{43017,43018,43019} Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways.{43020} Levels of globotetraosylceramides are elevated in fibroblasts from patients with salt and pepper syndrome, a neurocutaneous condition characterized by intellectual disability and hyper- and hypo-pigmented skin.{43021} This product contains globotetraosylceramides with primarily C24:0, C22:0, and 2-hydroxy C24:0 fatty acyl chains. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1068]

• Artikelnummer: CAY24881
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24881-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK