Glyco-Obeticholic Acid, CAS 863239-60-5

Formulation: A solid

Formal Name: N-[(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-24-oxocholan-24-yl]-glycine

Purity: ≥98%

Formula Markup: C28H47NO5

Formula Weight: 477,7

Shelf life (days): 1460

CAS Number: 863239-60-5

Notes: Glyco-obeticholic acid is an active metabolite of obeticholic acid (6-ECDCA; Item No. 11031), which is a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid (Item No. 10011286).{46303} Glyco-obeticholic acid is formed from obeticholic acid by glycine conjugation in the liver but can be reconverted back to obeticholic acid by microorganism-mediated deconjugation in the ileum and colon. It has been used as a precursor in the synthesis of bile acid analogs as agonists of the farnesoid X receptor (FXR) and TGR5.{45287}

• Artikelnummer: CAY28242-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28242-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK