Formulation: A crystalline solid
Formal Name: N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-glycine, monohydrate
Purity: ≥95%
Formula Markup: C26H43NO5 • H2O
Formula Weight: 467,6
Shelf life (days): 1460
CAS Number: 1079043-81-4
Notes: Glycodeoxycholic acid (GDCA) is a glycine-conjugated form of the secondary bile acid deoxycholic acid (Item Nos. 18231 / 20756).{48223} It induces a reversible, concentration-dependent reduction in myogenic tone in rats and decreases expression of the gene encoding the cytochrome P450 (CYP) isoform 7A1 (CYP7A1) in rabbits.{33912,33913} Serum levels of GDCA are elevated in non-surviving patients with acetaminophen-induced acute liver failure (AALF) compared with survivors.{33914} GDCA levels are also increased in the plasma of patients with asthma.{33911}