Hecogenin Acetate, CAS 915-35-5

Formulation: A crystalline solid

Formal Name: (3β,5α,25R)-3-(acetyloxy)-spirostan-12-one

Purity: ≥98%

Formula Markup: C29H44O5

Formula Weight: 472,7

Shelf life (days): 1460

CAS Number: 915-35-5

Notes: Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin (Item No. 21372) that has anthelmintic and antinociceptive properties.{42489,42490,42491} It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml).{42489} Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine (Item No. 21992), and prostaglandin E2 (PGE2; Item No. 14010) in mice.{42490} It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.{42491}

• Artikelnummer: CAY25977-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25977-5
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK