Isodeoxycholic Acid, CAS 566-17-6

Formulation: A solid

Formal Name: (5β,7α,12α)-7,12-dihydroxy-cholan-24-oic acid

Purity: ≥95%

Formula Markup: C24H40O4

Formula Weight: 392,6

Shelf life (days): 730

CAS Number: 566-17-6

Notes: Isodeoxycholic acid is a bile acid that is formed via epimerization of deoxycholic acid (DCA; Item Nos. 20756 / 18231) by intestinal bacteria.{54005} It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic acid (0.1%) inhibits spore germination induced by taurocholic acid (Item No. 16215) in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants to Vero cells.{54006} Plasma levels of isodeoxycholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.{54007}

• Artikelnummer: CAY29890-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29890-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK