Isoliquiritin, CAS 5041-81-6

Formulation: A crystalline solid

Formal Name: (2E)-1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-2-propen-1-one

Purity: ≥98%

Formula Markup: C21H22O9

Formula Weight: 418,4

Shelf life (days): 1460

CAS Number: 5041-81-6

Notes: Isoliquiritin is a flavonoid that has been found in G. uralensis roots and has diverse biological activities.{54056,54057,54058} It inhibits LPS-induced nitrite and prostaglandin E2 (PGE2; Item No. 14010) production in RAW 264.7 cells when used at a concentration of 1.6 µM.{54056} Isoliquiritin (5-500 µg/ml) inhibits tube formation by isolated rat aortic endothelial cells.{54057} In vivo, isoliquiritin reduces carmine content, a marker of blood vessel formation, and pouch fluid weight in a mouse model of adjuvant-induced pouch granuloma formation (ED50s = 1.46 and 0.771 mg/kg, respectively). It increases cortical, hippocampal, and hypothalamic serotonin (5-HT) and norepinephrine levels and decreases immobility time in the forced swim and tail suspension tests in mice when administered at doses ranging from 10 to 40 mg/kg.{54058}

• Artikelnummer: CAY30270-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30270-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK