Kuwanon C, CAS 62949-79-5

Formulation: A crystalline solid

Formal Name: 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C25H26O6

Formula Weight: 422,5

Shelf life (days): 1460

CAS Number: 62949-79-5

Notes: Kuwanon C is a prenylated flavone originally isolated from M. alba that has diverse biological activities, including antioxidant, antibacterial, antiproliferative, and neuroprotective properties.{57492} It scavenges DPPH (Item No. 14805) radicals in a cell-free assay (EC50 = 72.99 µg/ml).{57493} It is active against E. coli, S. typhimurium, S. epidermis, and S. aureus (MICs = 10, 25, 6.25, and 6.25 µg/ml, respectively) and inhibits the growth of P388 mouse lymphoma cancer cells (IC50 = 14 µg/ml).{57494,57495} Kuwanon C (30 mg/kg) improves motor coordination in a rotarod test and decreases neuronal loss in the substantia nigra pars compacta in a mouse model of MPTP-induced Parkinson's disease.{57496}

• Artikelnummer: CAY33421-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33421-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK