Leukotriene E4, CAS 75715-89-8

Formulation: A solution in ethanol

Formal Name: 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid

Purity: ≥97%

Formula Markup: C23H37NO5S

Formula Weight: 439,6

Shelf life (days): 365

CAS Number: 75715-89-8

Notes: Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone.{2236} It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A).{394} LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities characteristic of cysteinyl leukotrienes.{2236,396} Unlike LTC4 and LTD4, LTE4 accumulates in both plasma and urine. Therefore, urinary excretion of LTE4 is often used as an indicator of asthma.{1815,865,2064} In humans, basal levels of LTE4 range from 1-100 pg/mg creatinine. In asthmatic patients, urinary LTE4 levels increase to 80-1,000 pg/mg creatinine.{865}

• Artikelnummer: CAY20410-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20410-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK