Linoleoyl Glycine, CAS 2764-03-6

Formulation: A crystalline solid

Formal Name: N-9Z,12Z-1-oxo-octadecadien-1-yl-glycine

Purity: ≥98%

Formula Markup: C20H35NO3

Formula Weight: 337,5

Shelf life (days): 730

CAS Number: 2764-03-6

Notes: Arachidonyl glycine, the conjugate of arachidonic acid and glycine produced in mammalian brain, skin, and spinal cord, is a structural analog of anandamide (AEA) that is reported to have analgesic activities in whole animal experiments.{9578,9579,9589} It has poor affinity for the central cannabinoid (CB1) receptor, high-affinity for the G protein-coupled receptor GPR-18, and is metabolically regulated by fatty acid amide hydrolase (FAAH) activity.{15693} LinGly is an endogenous homolog of linoleoyl ethanolamide, an arachidonyl glycine. It inhibits the hydrolysis of AEA in FAAH-containing N18TG2 cell membranes with an IC50 value of ~25 µM, which is less potent than that of arachidonyl glycine (IC50 = 7 µM).{9589} The biological significance of LinGly has not yet been determined.

• Artikelnummer: CAY9000326-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000326-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK