Lyso-Monosialoganglioside GM2 (ammonium salt)

Formulation: A solid

Formal Name: (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-[N-acetyl-α-neuraminosyl-(2→3)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside, monoammonium salt

Purity: ≥98%

Formula Markup: C49H86N3O25 • NH4

Formula Weight: 1135,3

Shelf life (days): 1460

Notes: Lyso-monosialoganglioside GM2 (Lyso-GM2) is a form of ganglioside GM2 (Item No. 31710) that is lacking the fatty acyl group. Lyso-GM2 inhibits PKC in a cell-free assay (IC50 = 50 µM).{15202} Levels of lyso-GM2 are increased in the gray matter of postmortem brain samples from patients with Sandhoff disease or Tay-Sachs disease, as well as in a mouse model of Sandhoff disease.{38940,60286} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1543]

• Artikelnummer: CAY33073
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33073-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK