Murideoxycholic Acid, CAS 668-49-5

Formulation: A crystalline solid

Formal Name: 5β-3α,6β-dihydroxy-cholan-24-oic acid

Purity: ≥95%

Formula Markup: C24H40O4

Formula Weight: 392,6

Shelf life (days): 730

CAS Number: 668-49-5

Notes: Murideoxycholic acid (MDCA) is a secondary bile acid produced from α-muricholic acid (Item No. 20291) and β-muricholic acid (Item No. 20287).{45190} It is also a metabolite of lithocholic acid (Item No. 20253) in liver S9 fractions from humans and other species.{46202} MDCA prevents gallstone formation in hamsters fed a lithogenic diet but does not resolve gallstones in prairie dogs fed a high cholesterol diet.{37053,37054} Gallstones formed during MDCA administration after a high cholesterol diet are comprised of an insoluble calcium salt of murideoxycholyl taurine.{37054} In humans, MDCA is rapidly absorbed and is metabolized as an endogenous bile acid with a half-life of approximately 3.5 days.{37055}

• Artikelnummer: CAY20290-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20290-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK