N-(α-Linolenoyl) Tyrosine, CAS 259143-19-6

Formulation: A solution in ethanol

Formal Name: N-[(9Z,12Z,15Z)-1-oxo-9,12,15-octadecatrien-1-yl]-L-tyrosine

Purity: ≥98%

Formula Markup: C27H39NO4

Formula Weight: 441,6

Shelf life (days): 365

CAS Number: 259143-19-6

Notes: Certain chronic neurologic disorders, such as Parkinson’s disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons.{7161} N-(α-Linolenoyl) tyrosine (NALT) is a simple α-amide conjugate between the ω-3 essential fatty acid α-linolenate and the amino acid tyrosine. α-Linolenate is an important precursor to docosahexaenoic acid (DHA), a prominent brain polyunsaturated fatty acid, while tyrosine is the metabolic precursor for neuronal dopamine synthesis. NALT was prepared as a method for enhancing central nervous system (CNS) dopamine content by facilitated transport of the tyrosine precursor across the blood-brain barrier.{10323} In experimental rat models of dopamine insufficiency, NALT increased CNS dopamine levels and exhibited an activity profile consistent with an anti-Parkinson’s therapeutic agent.{10323}

• Artikelnummer: CAY10032-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10032-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK