Nocloprost, CAS 79360-43-3

Formulation: A solution in methyl acetate

Formal Name: 9β-chloro-11α,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid

Purity: ≥98%

Formula Markup: C22H37ClO4

Formula Weight: 401

Shelf life (days): 365

CAS Number: 79360-43-3

Notes: Nocloprost is a stable prostaglandin E2 analog with gastroprotective and ulcer-healing properties. As a weak acid (pKa = 5), it accumulates in the gastric mucosa at low pH and can prevent the formation of gastric lesions in rats when administered intragastrically 30 minutes before 100% ethanol, acidified aspirin, acidified taurocholate, water immersion, or restraint stress (ID50s = 0.25, 0.58, 0.06 and 0.12 μg/kg, respectively).{21339} Additionally, nocloprost has been used to inhibit evoked acetylcholine release from isolated human bronchi (IC50 = 4 nM) to study factors that regulate human airway smooth muscle tone and secretion.{21338}

• Artikelnummer: CAY10988-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10988-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: Reinstoffe