Oleoyl Ethanolamide, CAS 111-58-0

Formulation: A crystalline solid

Formal Name: N-(2-hydroxyethyl)-9Z-octadecenamide

Purity: ≥98%

Formula Markup: C20H39NO2

Formula Weight: 325,5

Shelf life (days): 365

CAS Number: 111-58-0

Notes: Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate.{5291} It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue,{2874} but its biosynthesis is reduced in the intestine of rats following food deprivation.{9302} OEA is an endogenous, potent agonist for PPARα, exhibiting an EC50 value of 120 nM in a transactivation assay.{11423} Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice.{9302,11423} These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.

• Artikelnummer: CAY90265-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 90265-1
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK
• Methode: Reinstoffe