Oleoyl Ethanolamide-d4, CAS 946524-36-3

Formulation: A solution in ethanol

Formal Name: N-(2-hydroxyethyl-1',1,2,2'-d4)-9Z-octadecenamide

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C20H35D4NO2

Formula Weight: 329,6

Shelf life (days): 365

CAS Number: 946524-36-3

Notes: Oleoyl ethanolamide-d4 contains four deuterium atoms at the hydroxyethyl 1,1',2, and 2' positions. It is intended for use as an internal standard for the quantification of oleoyl ethanolamide by GC- or LC-mass spectrometry. Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate.{5291} It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue,{2874} but its biosynthesis is reduced in the intestine of rats following food deprivation.{9302} OEA is an endogenous, potent agonist for PPARα, exhibiting an EC50 value of 120 nM in a transactivation assay.{11423} Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice.{9302,11423} These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.

• Artikelnummer: CAY9000552-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000552-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung