Formulation: A crystalline solid
Formal Name: cholest-5-ene-3b,20,22R-triol
Purity: ≥95%
Formula Markup: C27H46O3
Formula Weight: 418,7
Shelf life (days): 730
CAS Number: 596-94-1
Notes: Naturally occurring oxysterols are products of cholesterol oxidation that can stimulate the hedgehog (Hh) signaling pathway in target cells associated with cardiovascular disease and with bone formation.{18498} Depending on the target cell, activation of Hh signaling can modulate inflammatory responses to additional atherogenic factors such as lesion-producing macrophages or enable osteoblast differentiation.{18500,18499} Oxy-16 is a synthetic oxysterol compound that may function as an antagonist of hedgehog activity. Published data regarding its efficacy remains forthcoming.