PAF C-18-d4

Formulation: A solution in ethanol

Formal Name: 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine-9,9,10,10-d4

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C28H54D4NO7P

Formula Weight: 555,7

Shelf life (days): 730

Notes: PAF C-18-d4 contains four deuterium atoms at the 9, 9', 10, and 10' positions. It is intended for use as an internal standard for the quantification of PAF C-18 by GC- or LC-mass spectrometry. PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the “remodeling” and 'de novo' pathways.{939} It is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages.{3786} PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and enhances the spreading of plated macrophages.{640} Pathological processes involving PAF include necrotizing enterocolitis,{5841} inflammation, asthma, and allergy.{303}

• Artikelnummer: CAY10010229-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10010229-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung